{"id":11440,"date":"2025-05-26T17:40:11","date_gmt":"2025-05-26T15:40:11","guid":{"rendered":"https:\/\/www.kliinikum.ee\/yhendlabor\/?page_id=11440"},"modified":"2026-05-22T14:42:45","modified_gmt":"2026-05-22T12:42:45","slug":"neerupealise-koore-vastased-antikehad-s-aaa-ab","status":"publish","type":"page","link":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/autoimmuunuuringud\/neerupealise-koore-vastased-antikehad-s-aaa-ab\/","title":{"rendered":"Neerupealise koore vastane IgG (S-AAA IgG)"},"content":{"rendered":"\n

Immuunanal\u00fc\u00fcsi osakond<\/em><\/p>\n\n\n\n

Neerupealise koore vastased IgG antikehad<\/strong> on seerumis esinevad autoantikehad (anti<\/em>-adrenocortical antibodies<\/em>, AAA IgG), mille sihtantigeenid on ts\u00fctokroom P450 steroidogeensed ens\u00fc\u00fcmid, peamiselt 21-h\u00fcdroks\u00fclaas.<\/p>\n\n\n\n

Uuritav materjal, selle v\u00f5tmine, saatmine ja s\u00e4ilitamine<\/strong><\/p>\n\n\n\n

<\/td>Katsuti<\/strong><\/td> Geeli ja h\u00fc\u00fcbimisaktivaatoriga katsuti (punane kollase r\u00f5ngaga v\u00f5i kollane kork)<\/td><\/tr>
<\/td>S\u00e4ilivus<\/strong><\/td> Seerum +4 \u00b0C kaks p\u00e4eva, -20 \u00b0C kaks kuud <\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Anal\u00fc\u00fcsi tegemise aeg:<\/strong> kord n\u00e4dalas<\/p>\n\n\n\n

Anal\u00fc\u00fcsimeetod:<\/strong> kaudne immuunfluorestsentsmeetod (IIF)<\/p>\n\n\n\n

Vastuse vorm<\/strong><\/p>\n\n\n\n

Positiivne\/negatiivne<\/p>\n\n\n\n

N\u00e4idustus ja kliiniline t\u00e4hendus<\/strong><\/p>\n\n\n\n

Addisoni t\u00f5ve ja autoimmuunsete (eriti ovariaalfunktsiooni h\u00e4iretega kaasnevate) pol\u00fcendokrinopaatiate diagnostika, samuti nimetatud haiguste tekke riski hindamine haigete l\u00e4hisugulastel ja insuliins\u00f5ltuva diabeedi (IDDM) ehk 1. t\u00fc\u00fcpi diabeedi ning autoimmuunse t\u00fcreoidiidiga patsientidel.<\/p>\n\n\n\n

Neerupealise koore vastased antikehad on k\u00f5rge spetsiifilisusega autoimmuunse Addisoni t\u00f5ve ning autoimmuunsete pol\u00fcglandulaars\u00fcndroomide(APS I ja APS II) markerid. Need esinevad 20\u201380% Addisoni t\u00f5ve juhtudest, kusjuures antikehade leidumine on t\u00f5en\u00e4olisem kaasneva pol\u00fcglandulaars\u00fcndroomi korral (APS I puhul 60\u201380%, APS II puhul 25\u201340%). Primaarse autoimmuunse ovariaalpuudulikkusega Addisoni t\u00f5ve haigetel leitakse neerupealise koore antikehi kuni 100% uuritutest. Nendel antikehadel on ka prognostiline t\u00e4hendus. On v\u00f5imalik, et antikehade teke eelneb kliiniliselt manifesteerunud haigusele.<\/p>\n\n\n\n

Koostaja: Anet Laanesoo, Kaja Metsk\u00fcla
Muudetud 27.04.2026<\/p>\n","protected":false},"excerpt":{"rendered":"

Immuunanal\u00fc\u00fcsi osakond Neerupealise koore vastased IgG antikehad on seerumis esinevad autoantikehad (anti-adrenocortical antibodies, AAA IgG), mille sihtantigeenid on ts\u00fctokroom P450 steroidogeensed ens\u00fc\u00fcmid, peamiselt 21-h\u00fcdroks\u00fclaas. Uuritav materjal, selle v\u00f5tmine, saatmine ja s\u00e4ilitamine Katsuti  Geeli ja h\u00fc\u00fcbimisaktivaatoriga katsuti (punane kollase r\u00f5ngaga v\u00f5i kollane kork) S\u00e4ilivus  Seerum +4 \u00b0C kaks p\u00e4eva, -20 \u00b0C kaks kuud Anal\u00fc\u00fcsi tegemise aeg: […]<\/p>\n","protected":false},"author":38,"featured_media":0,"parent":7253,"menu_order":12,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-11440","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nNeerupealise koore vastane IgG (S-AAA IgG) - \u00dchendlabor<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/autoimmuunuuringud\/neerupealise-koore-vastased-antikehad-s-aaa-ab\/\" \/>\n<meta property=\"og:locale\" content=\"et_EE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Neerupealise koore vastane IgG (S-AAA IgG) - \u00dchendlabor\" \/>\n<meta property=\"og:description\" content=\"Immuunanal\u00fc\u00fcsi osakond Neerupealise koore vastased IgG antikehad on seerumis esinevad autoantikehad (anti-adrenocortical antibodies, AAA IgG), mille sihtantigeenid on ts\u00fctokroom P450 steroidogeensed ens\u00fc\u00fcmid, peamiselt 21-h\u00fcdroks\u00fclaas. 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