{"id":11953,"date":"2025-06-29T22:54:18","date_gmt":"2025-06-29T20:54:18","guid":{"rendered":"https:\/\/www.kliinikum.ee\/yhendlabor\/?page_id=11953"},"modified":"2025-12-21T18:11:12","modified_gmt":"2025-12-21T16:11:12","slug":"retikulotsuutide-paneel-b-ret","status":"publish","type":"page","link":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hematoloogilised-uuringud\/retikulotsuutide-paneel-b-ret\/","title":{"rendered":"Retikulots\u00fc\u00fctide paneel (B-Ret)"},"content":{"rendered":"\n

Kliinilise keemia ja laboratoorse hematoloogia osakond<\/em><\/p>\n\n\n\n

Retikulots\u00fc\u00fcdid <\/strong>on mittek\u00fcpsed er\u00fctrots\u00fc\u00fcdid. Nad sisaldavad ribosomaalse RNA j\u00e4\u00e4ke punavereloome eellasrakkudest. Retikulots\u00fc\u00fcdi-staadium veres kestab umbes kaks p\u00e4eva, mille v\u00e4ltel retikulots\u00fc\u00fcdi k\u00fcpsedes ribosomaalne substants kaob.<\/p>\n\n\n\n

Retikulots\u00fc\u00fcte saab jaotada l\u00e4bivooluts\u00fctomeetrial k\u00fcpsusastme alusel kolmeks alapopulatsiooniks: HFR (high fluoresence reticulocytes)<\/em> \u2013v\u00e4iksema k\u00fcpsusastmega retikulots\u00fc\u00fcdid, MFR (medium<\/em> fluoresence reticulocytes)<\/em> \u2013 keskmise k\u00fcpsusastmega retikulots\u00fc\u00fcdid ja  LFR (low fluorescence reticulocytes)<\/em> \u2013 suurema k\u00fcpsusastmega retikulots\u00fc\u00fcdid. HFR ja MFR annavad kokku ebak\u00fcpsete retikulots\u00fc\u00fctide fraktsiooni (immature reticulocyte fraction, IRF)<\/em>.<\/p>\n\n\n\n

Retikulots\u00fc\u00fctide hemoglobiin (Ret-Hb) hindab hemoglobiini s\u00fcnteesi ja raua biosaadavust er\u00fctropoeesis viimase 24\u201348 tunni jooksul, olles seega varajaseks rauadefitsiidi markeriks.<\/p>\n\n\n\n

Uuritav materjal, selle v\u00f5tmine, saatmine ja s\u00e4ilitamine<\/strong><\/p>\n\n\n\n

<\/td>Katsuti<\/strong><\/td>K2E\/K3E-katsuti (lilla kork)<\/td><\/tr>
<\/td>S\u00e4ilivus<\/strong><\/td>Veri toatemperatuuril kuus tundi, +4 \u00b0C kaks p\u00e4eva<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Anal\u00fc\u00fcsi tegemise aeg: <\/strong>\u00f6\u00f6p\u00e4evaringselt<\/p>\n\n\n\n

Anal\u00fc\u00fcsimeetod: <\/strong>l\u00e4bivooluts\u00fctomeetria automaatanal\u00fcsaatoril<\/p>\n\n\n\n

Referentsv\u00e4\u00e4rtused<\/strong><\/p>\n\n\n\n

<\/td>\u2265 18 a<\/strong><\/td>Ret<\/td>0,5\u20132,5%<\/td><\/tr>
<\/td> <\/td> <\/td>50\u2013100 x 10E9\/L<\/td><\/tr>
<\/td> <\/td>IRF<\/td>2,7\u201314,9%<\/td><\/tr>
<\/td> <\/td>Ret-Hb<\/td>29,7\u201335,4 pg<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

N\u00e4idustus ja kliiniline t\u00e4hendus<\/strong><\/p>\n\n\n\n

Er\u00fctropoeesi aktiivsuse hindamine.<\/p>\n\n\n\n

Retikulots\u00fctoos:<\/em> hemol\u00fc\u00fctiline aneemia; verekaotuse j\u00e4rgne seisund; pol\u00fcts\u00fcteemia; er\u00fctropoetiinravi; rasedus. M\u00f6\u00f6duvat retikulots\u00fc\u00fctide arvu t\u00f5usu v\u00f5ib n\u00e4ha ka p\u00e4rast ravi alustamist rauapreparaatide, vitamiin B12 v\u00f5i foolhappega.<\/p>\n\n\n\n

Retikulots\u00fctopeenia: <\/em>raua, vitamiin B12 ja folaatide defitsiit; er\u00fctropoetiini taseme langus (nt krooniline neerupuudulikkus), vereloome haigused nagu aplastiline aneemia, m\u00fcelod\u00fcsplastiline s\u00fcndroom, m\u00fcelofibroos, leukeemia; luu\u00fcdi supressiooni p\u00f5hjustavate ravimite tarvitamine.<\/p>\n\n\n\n

IRF<\/em> v\u00f5imaldab hinnata aneemia t\u00fc\u00fcpi, ravitulemust ja luu\u00fcdi seisundit p\u00e4rast keemiaravi v\u00f5i vereloome t\u00fcvirakkude siirdamist. IRF rakkude hulk suureneb p\u00e4rast keemiaravi ning  vereloome t\u00fcvirakkude siirdamist kiiremini kui retikulots\u00fc\u00fctide \u00fcldarv.<\/p>\n\n\n\n

Retikulots\u00fc\u00fctide hemoglobiin (Ret-Hb)<\/em> on madal nii funktsionaalse kui absoluutse rauadefitsiidi korral. Ret-Hb on v\u00e4henenud ka talasseemiate, heemi s\u00fcnteesi h\u00e4irete ning osade m\u00fcelod\u00fcsplastiliste s\u00fcndroomide korral. Retikulots\u00fc\u00fctide hemoglobiini saab kasutada ravi monitoorimiseks er\u00fctropoetiini (EPO) ja\/v\u00f5i intravenoossete raua preparaatidega. Ret-Hb t\u00f5useb raua intravenoosse manustamise korral 2.\u20134. p\u00e4eval p\u00e4rast ravi alustamist.<\/p>\n\n\n\n

Ret-Hb tulemuse t\u00f5lgendamisel tuleks arvestada ka teisi raua ainevahetuse biokeemilisi markereid nagu ferritiin, transferriini k\u00fcllastus, transferriini lahustuvad retseptorid.<\/p>\n\n\n\n

Vt ka: Hemogramm 5-osalise leukogrammiga<\/a> <\/p>\n\n\n\n

Koostajad: Signe Feodorov, Katrin Reimand, Triin Paabo
Muudetud 24.01.2023<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Kliinilise keemia ja laboratoorse hematoloogia osakond Retikulots\u00fc\u00fcdid on mittek\u00fcpsed er\u00fctrots\u00fc\u00fcdid. Nad sisaldavad ribosomaalse RNA j\u00e4\u00e4ke punavereloome eellasrakkudest. Retikulots\u00fc\u00fcdi-staadium veres kestab umbes kaks p\u00e4eva, mille v\u00e4ltel retikulots\u00fc\u00fcdi k\u00fcpsedes ribosomaalne substants kaob. Retikulots\u00fc\u00fcte saab jaotada l\u00e4bivooluts\u00fctomeetrial k\u00fcpsusastme alusel kolmeks alapopulatsiooniks: HFR (high fluoresence reticulocytes) \u2013v\u00e4iksema k\u00fcpsusastmega retikulots\u00fc\u00fcdid, MFR (medium fluoresence reticulocytes) \u2013 keskmise k\u00fcpsusastmega retikulots\u00fc\u00fcdid ja  LFR […]<\/p>\n","protected":false},"author":38,"featured_media":0,"parent":7265,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-11953","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nRetikulots\u00fc\u00fctide paneel (B-Ret) - \u00dchendlabor<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hematoloogilised-uuringud\/retikulotsuutide-paneel-b-ret\/\" \/>\n<meta property=\"og:locale\" content=\"et_EE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Retikulots\u00fc\u00fctide paneel (B-Ret) - \u00dchendlabor\" \/>\n<meta property=\"og:description\" content=\"Kliinilise keemia ja laboratoorse hematoloogia osakond Retikulots\u00fc\u00fcdid on mittek\u00fcpsed er\u00fctrots\u00fc\u00fcdid. 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Nad sisaldavad ribosomaalse RNA j\u00e4\u00e4ke punavereloome eellasrakkudest. Retikulots\u00fc\u00fcdi-staadium veres kestab umbes kaks p\u00e4eva, mille v\u00e4ltel retikulots\u00fc\u00fcdi k\u00fcpsedes ribosomaalne substants kaob. 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