{"id":12033,"date":"2025-07-01T15:52:05","date_gmt":"2025-07-01T13:52:05","guid":{"rendered":"https:\/\/www.kliinikum.ee\/yhendlabor\/?page_id=12033"},"modified":"2025-11-26T18:30:15","modified_gmt":"2025-11-26T16:30:15","slug":"dehudroepiandrosteroonsulfaat-sp-dheas","status":"publish","type":"page","link":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hormoonid-jm-immuunuuringud\/dehudroepiandrosteroonsulfaat-sp-dheas\/","title":{"rendered":"Deh\u00fcdroepiandrosteroonsulfaat (S,P-DHEAS)"},"content":{"rendered":"\n

Kliinilise keemia ja laboratoorse hematoloogia osakond<\/em><\/p>\n\n\n\n

Deh\u00fcdroepiandrosteroonsulfaat (DHEAS)<\/strong> on k\u00f5ige suuremal hulgal tsirkuleeriv steroidhormoon, mis p\u00e4rineb valdavalt neerupealiste koorest. \u00dcle 90% hormoonist on seotud albumiiniga ja vaid v\u00e4hesel m\u00e4\u00e4ral suguhormoone siduva globuliiniga. Ainult 10\u201315% t\u00e4iskasvanud meeste DHEAS-st s\u00fcnteesitakse testistes. DHEAS konverteeritakse bioloogiliselt aktiivseteks andro- ja \u00f6strogeenideks ja on seega viimaste reservuaariks organismis. Erinevalt deh\u00fcdroepiandrosteroonist (DHEA) ei oma DHEAS sekretsioon \u00f6\u00f6p\u00e4evar\u00fctmi ning on stabiilsem, seet\u00f5ttu kasutatakse m\u00e4\u00e4ramiseks just DHEAS-i, mis k\u00f5ige paremini iseloomustab neerupealistes androgeenide s\u00fcnteesi.<\/p>\n\n\n\n

Uuritav materjal, selle v\u00f5tmine, saatmine ja s\u00e4ilitamine<\/strong><\/p>\n\n\n\n

<\/td>Katsuti<\/strong><\/td>Geeli ja h\u00fc\u00fcbimisaktivaatoriga katsuti (punane kollase r\u00f5ngaga v\u00f5i kollane kork) v\u00f5i geeliga LH-katsuti (roheline kollase r\u00f5ngaga v\u00f5i heleroheline kork)<\/td><\/tr>
<\/td>S\u00e4ilivus<\/strong><\/td>Seerum\/plasma toatemperatuuril viis p\u00e4eva, +4 \u00b0C kaks n\u00e4dalat, -20 \u00b0C \u00fcks aasta<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Anal\u00fc\u00fcsi tegemise aeg:<\/strong> t\u00f6\u00f6p\u00e4eviti<\/p>\n\n\n\n

Anal\u00fc\u00fcsimeetod: <\/strong>elektrokemoluminestsents-immuunmeetod (ECLIA)<\/p>\n\n\n\n

Referentsv\u00e4\u00e4rtused<\/strong><\/p>\n\n\n\n

<\/td>< 1 n<\/strong><\/td>2,93\u201316,5 \u03bcmol\/L<\/td><\/td><\/tr>
<\/td>1 n \u2013 < 1 k<\/strong><\/td>0,86\u201311,7 \u03bcmol\/L<\/td><\/td><\/tr>
<\/td>1 k \u2013 < 1 a<\/strong><\/td>0,09\u20133,35 \u03bcmol\/L<\/td><\/td><\/tr>
<\/td>1 a \u2013 < 5 a<\/strong><\/td>0,01\u20130,53 \u03bcmol\/L<\/td><\/td><\/tr>
<\/td>5 a \u2013 < 10 a<\/strong><\/td>0,08\u20132,31 \u03bcmol\/L<\/td><\/td><\/tr>
<\/td>10 a \u2013 < 15 a<\/strong><\/td>M 0,66\u20136,70 \u03bcmol\/L\u00a0\u00a0 \u00a0\u00a0<\/td>N\u00a0 0,92\u20137,60 \u03bcmol\/L<\/td><\/tr>
<\/td>15 a \u2013 < 20 a<\/strong><\/td>M 1,91\u201313,4 \u03bcmol\/L \u00a0\u00a0\u00a0\u00a0<\/td>N\u00a0 1,77\u20139,99 \u03bcmol\/L<\/td><\/tr>
<\/td>20 a \u2013 < 25 a<\/strong><\/td>M 5,73\u201313,4 \u03bcmol\/L \u00a0\u00a0\u00a0\u00a0<\/td>N\u00a0 4,02\u201311,0 \u03bcmol\/L<\/td><\/tr>
<\/td>25 a \u2013 < 35 a<\/strong><\/td>M 4,34\u201312,2 \u03bcmol\/L\u00a0\u00a0 \u00a0\u00a0<\/td>N\u00a0 2,68\u20139,23 \u03bcmol\/L<\/td><\/tr>
<\/td>35 a \u2013 < 45 a<\/strong><\/td>M 2,41\u201311,6 \u03bcmol\/L\u00a0 \u00a0\u00a0\u00a0<\/td>N\u00a0 1,65\u20139,15 \u03bcmol\/L<\/td><\/tr>
<\/td>45 a \u2013 < 55 a<\/strong><\/td>M 1,20\u20138,98 \u03bcmol\/L \u00a0\u00a0\u00a0\u00a0<\/td>N\u00a0 0,96\u20136,95 \u03bcmol\/L<\/td><\/tr>
<\/td>55 a \u2013 < 65 a<\/strong><\/td>M 1,40\u20138,01 \u03bcmol\/L\u00a0\u00a0 \u00a0\u00a0<\/td>N\u00a0 0,51\u20135,56 \u03bcmol\/L<\/td><\/tr>
<\/td>65 a \u2013 < 75 a<\/strong><\/td>M 0,91\u20136,76 \u03bcmol\/L \u00a0\u00a0\u00a0\u00a0<\/td>N\u00a0 0,26\u20136,68 \u03bcmol\/L<\/td><\/tr>
<\/td>\u2265 75 a<\/strong><\/td>M 0,44\u20133,34 \u03bcmol\/L\u00a0\u00a0 \u00a0\u00a0<\/td>N\u00a0 0,33\u20134,18 \u03bcmol\/L<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

N\u00e4idustus ja kliiniline t\u00e4hendus<\/strong><\/p>\n\n\n\n

DHEAS anal\u00fc\u00fcsi kasutatakse h\u00fcperandrogenismi, hirsutismi, virilismi ja hilinenud puberteedi p\u00f5hjuste selgitamisel, samuti neerupealiste h\u00fcperplaasia ja kasvajate diagnostikas.<\/p>\n\n\n\n

Neerupealiste h\u00fcperplaasia korral on DHEAS tase t\u00f5usnud kas tugeva adrenokortikotroopse hormooni (ACTH) stimulatsiooni v\u00f5i m\u00f5ne ens\u00fc\u00fcmdefekti t\u00f5ttu, mis v\u00f5ib viia erineval tasemel maskuliniseerumisele. Pol\u00fcts\u00fcstiliste ovaariumide s\u00fcndroomi (PCOS) korral v\u00f5ib DHEAS tase olla t\u00f5usnud.<\/p>\n\n\n\n

Neerupealiste puudulikkus v\u00f5i h\u00fcpof\u00fc\u00fcsi vaegtalitus p\u00f5hjustavad DHEAS taseme langust.<\/p>\n\n\n\n

DHEAS hulk allub albumiini kontsentratsiooni k\u00f5ikumistele. Oraalsete \u00f6strogeenide manustamine v\u00f5ib p\u00f5hjustada DHEAS taseme langust, ravi ACTH-ga aga t\u00f5usu.<\/p>\n\n\n\n

Koostajad: Rain Lehtme, Kaja Vaagen
Muudetud 07.02.2023<\/p>\n","protected":false},"excerpt":{"rendered":"

Kliinilise keemia ja laboratoorse hematoloogia osakond Deh\u00fcdroepiandrosteroonsulfaat (DHEAS) on k\u00f5ige suuremal hulgal tsirkuleeriv steroidhormoon, mis p\u00e4rineb valdavalt neerupealiste koorest. \u00dcle 90% hormoonist on seotud albumiiniga ja vaid v\u00e4hesel m\u00e4\u00e4ral suguhormoone siduva globuliiniga. Ainult 10\u201315% t\u00e4iskasvanud meeste DHEAS-st s\u00fcnteesitakse testistes. DHEAS konverteeritakse bioloogiliselt aktiivseteks andro- ja \u00f6strogeenideks ja on seega viimaste reservuaariks organismis. Erinevalt deh\u00fcdroepiandrosteroonist (DHEA) […]<\/p>\n","protected":false},"author":38,"featured_media":0,"parent":7271,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-12033","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nDeh\u00fcdroepiandrosteroonsulfaat (S,P-DHEAS) - \u00dchendlabor<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hormoonid-jm-immuunuuringud\/dehudroepiandrosteroonsulfaat-sp-dheas\/\" \/>\n<meta property=\"og:locale\" content=\"et_EE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Deh\u00fcdroepiandrosteroonsulfaat (S,P-DHEAS) - \u00dchendlabor\" \/>\n<meta property=\"og:description\" content=\"Kliinilise keemia ja laboratoorse hematoloogia osakond Deh\u00fcdroepiandrosteroonsulfaat (DHEAS) on k\u00f5ige suuremal hulgal tsirkuleeriv steroidhormoon, mis p\u00e4rineb valdavalt neerupealiste koorest. \u00dcle 90% hormoonist on seotud albumiiniga ja vaid v\u00e4hesel m\u00e4\u00e4ral suguhormoone siduva globuliiniga. Ainult 10\u201315% t\u00e4iskasvanud meeste DHEAS-st s\u00fcnteesitakse testistes. DHEAS konverteeritakse bioloogiliselt aktiivseteks andro- ja \u00f6strogeenideks ja on seega viimaste reservuaariks organismis. Erinevalt deh\u00fcdroepiandrosteroonist (DHEA) […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hormoonid-jm-immuunuuringud\/dehudroepiandrosteroonsulfaat-sp-dheas\/\" \/>\n<meta property=\"og:site_name\" content=\"\u00dchendlabor\" \/>\n<meta property=\"article:modified_time\" content=\"2025-11-26T16:30:15+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutit\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.kliinikum.ee\\\/yhendlabor\\\/kasiraamat\\\/hormoonid-jm-immuunuuringud\\\/dehudroepiandrosteroonsulfaat-sp-dheas\\\/\",\"url\":\"https:\\\/\\\/www.kliinikum.ee\\\/yhendlabor\\\/kasiraamat\\\/hormoonid-jm-immuunuuringud\\\/dehudroepiandrosteroonsulfaat-sp-dheas\\\/\",\"name\":\"Deh\u00fcdroepiandrosteroonsulfaat (S,P-DHEAS) - \u00dchendlabor\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.kliinikum.ee\\\/yhendlabor\\\/#website\"},\"datePublished\":\"2025-07-01T13:52:05+00:00\",\"dateModified\":\"2025-11-26T16:30:15+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.kliinikum.ee\\\/yhendlabor\\\/kasiraamat\\\/hormoonid-jm-immuunuuringud\\\/dehudroepiandrosteroonsulfaat-sp-dheas\\\/#breadcrumb\"},\"inLanguage\":\"et\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.kliinikum.ee\\\/yhendlabor\\\/kasiraamat\\\/hormoonid-jm-immuunuuringud\\\/dehudroepiandrosteroonsulfaat-sp-dheas\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.kliinikum.ee\\\/yhendlabor\\\/kasiraamat\\\/hormoonid-jm-immuunuuringud\\\/dehudroepiandrosteroonsulfaat-sp-dheas\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.kliinikum.ee\\\/yhendlabor\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"K\u00e4siraamat\",\"item\":\"https:\\\/\\\/www.kliinikum.ee\\\/yhendlabor\\\/kasiraamat\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Hormoonid jm immuunuuringud\",\"item\":\"https:\\\/\\\/www.kliinikum.ee\\\/yhendlabor\\\/kasiraamat\\\/hormoonid-jm-immuunuuringud\\\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Deh\u00fcdroepiandrosteroonsulfaat (S,P-DHEAS)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.kliinikum.ee\\\/yhendlabor\\\/#website\",\"url\":\"https:\\\/\\\/www.kliinikum.ee\\\/yhendlabor\\\/\",\"name\":\"\u00dchendlabor\",\"description\":\"Hoolivus, Uuendusmeelsus, P\u00e4devus ja Usaldusv\u00e4\u00e4rsus\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.kliinikum.ee\\\/yhendlabor\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"et\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Deh\u00fcdroepiandrosteroonsulfaat (S,P-DHEAS) - \u00dchendlabor","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hormoonid-jm-immuunuuringud\/dehudroepiandrosteroonsulfaat-sp-dheas\/","og_locale":"et_EE","og_type":"article","og_title":"Deh\u00fcdroepiandrosteroonsulfaat (S,P-DHEAS) - \u00dchendlabor","og_description":"Kliinilise keemia ja laboratoorse hematoloogia osakond Deh\u00fcdroepiandrosteroonsulfaat (DHEAS) on k\u00f5ige suuremal hulgal tsirkuleeriv steroidhormoon, mis p\u00e4rineb valdavalt neerupealiste koorest. \u00dcle 90% hormoonist on seotud albumiiniga ja vaid v\u00e4hesel m\u00e4\u00e4ral suguhormoone siduva globuliiniga. Ainult 10\u201315% t\u00e4iskasvanud meeste DHEAS-st s\u00fcnteesitakse testistes. DHEAS konverteeritakse bioloogiliselt aktiivseteks andro- ja \u00f6strogeenideks ja on seega viimaste reservuaariks organismis. Erinevalt deh\u00fcdroepiandrosteroonist (DHEA) […]","og_url":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hormoonid-jm-immuunuuringud\/dehudroepiandrosteroonsulfaat-sp-dheas\/","og_site_name":"\u00dchendlabor","article_modified_time":"2025-11-26T16:30:15+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"2 minutit"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hormoonid-jm-immuunuuringud\/dehudroepiandrosteroonsulfaat-sp-dheas\/","url":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hormoonid-jm-immuunuuringud\/dehudroepiandrosteroonsulfaat-sp-dheas\/","name":"Deh\u00fcdroepiandrosteroonsulfaat (S,P-DHEAS) - \u00dchendlabor","isPartOf":{"@id":"https:\/\/www.kliinikum.ee\/yhendlabor\/#website"},"datePublished":"2025-07-01T13:52:05+00:00","dateModified":"2025-11-26T16:30:15+00:00","breadcrumb":{"@id":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hormoonid-jm-immuunuuringud\/dehudroepiandrosteroonsulfaat-sp-dheas\/#breadcrumb"},"inLanguage":"et","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hormoonid-jm-immuunuuringud\/dehudroepiandrosteroonsulfaat-sp-dheas\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hormoonid-jm-immuunuuringud\/dehudroepiandrosteroonsulfaat-sp-dheas\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.kliinikum.ee\/yhendlabor\/"},{"@type":"ListItem","position":2,"name":"K\u00e4siraamat","item":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/"},{"@type":"ListItem","position":3,"name":"Hormoonid jm immuunuuringud","item":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/hormoonid-jm-immuunuuringud\/"},{"@type":"ListItem","position":4,"name":"Deh\u00fcdroepiandrosteroonsulfaat (S,P-DHEAS)"}]},{"@type":"WebSite","@id":"https:\/\/www.kliinikum.ee\/yhendlabor\/#website","url":"https:\/\/www.kliinikum.ee\/yhendlabor\/","name":"\u00dchendlabor","description":"Hoolivus, Uuendusmeelsus, P\u00e4devus ja Usaldusv\u00e4\u00e4rsus","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.kliinikum.ee\/yhendlabor\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"et"}]}},"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"Kadi Siigur","author_link":"https:\/\/www.kliinikum.ee\/yhendlabor\/author\/kadisi\/"},"uagb_comment_info":0,"uagb_excerpt":"Kliinilise keemia ja laboratoorse hematoloogia osakond Deh\u00fcdroepiandrosteroonsulfaat (DHEAS) on k\u00f5ige suuremal hulgal tsirkuleeriv steroidhormoon, mis p\u00e4rineb valdavalt neerupealiste koorest. \u00dcle 90% hormoonist on seotud albumiiniga ja vaid v\u00e4hesel m\u00e4\u00e4ral suguhormoone siduva globuliiniga. Ainult 10\u201315% t\u00e4iskasvanud meeste DHEAS-st s\u00fcnteesitakse testistes. DHEAS konverteeritakse bioloogiliselt aktiivseteks andro- ja \u00f6strogeenideks ja on seega viimaste reservuaariks organismis. Erinevalt deh\u00fcdroepiandrosteroonist (DHEA)…","_links":{"self":[{"href":"https:\/\/www.kliinikum.ee\/yhendlabor\/wp-json\/wp\/v2\/pages\/12033","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.kliinikum.ee\/yhendlabor\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.kliinikum.ee\/yhendlabor\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.kliinikum.ee\/yhendlabor\/wp-json\/wp\/v2\/users\/38"}],"replies":[{"embeddable":true,"href":"https:\/\/www.kliinikum.ee\/yhendlabor\/wp-json\/wp\/v2\/comments?post=12033"}],"version-history":[{"count":0,"href":"https:\/\/www.kliinikum.ee\/yhendlabor\/wp-json\/wp\/v2\/pages\/12033\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.kliinikum.ee\/yhendlabor\/wp-json\/wp\/v2\/pages\/7271"}],"wp:attachment":[{"href":"https:\/\/www.kliinikum.ee\/yhendlabor\/wp-json\/wp\/v2\/media?parent=12033"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}