{"id":9925,"date":"2024-10-10T14:21:34","date_gmt":"2024-10-10T12:21:34","guid":{"rendered":"https:\/\/www.kliinikum.ee\/yhendlabor\/?page_id=9925"},"modified":"2025-12-21T17:25:39","modified_gmt":"2025-12-21T15:25:39","slug":"ferritiin-sp-fer","status":"publish","type":"page","link":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/aneemia-uuringud\/ferritiin-sp-fer\/","title":{"rendered":"Ferritiin (S,P-Fer)"},"content":{"rendered":"\n

Kliinilise keemia ja laboratoorse hematoloogia osakond<\/em><\/p>\n\n\n\n

Ferritiin <\/strong>on rauda sisaldav intratsellulaarne valk, mis on organismi raua depoovorm. Ferritiini on k\u00f5ige enam hepatots\u00fc\u00fctides ning maksa, p\u00f5rna ja luu\u00fcdi makrofaagides. Seda on samuti l\u00fcmfots\u00fc\u00fctides, fibroblastides ja k\u00fcpsevates er\u00fctroblastides. V\u00e4hesel m\u00e4\u00e4ral tsirkuleerib ferritiini veres ja kuna seerumi ferritiin p\u00e4rineb p\u00f5hiliselt rauadepoodest, siis on seerumi ferritiini v\u00e4\u00e4rtus rauadepoode t\u00e4itumuse \u00fcks adekvaatsemaid n\u00e4itajaid ega s\u00f5ltu transferriiniga seotud raua hulgast. Madal ferritiininivoo on alati seotud rauadepoode v\u00e4hesuse v\u00f5i puudumisega. Rauapuuduse korral langeb ferritiini tase v\u00e4ga varajases faasis enne aneemia kujunemist. Ferritiin on ka \u00e4geda faasi valk \u2013 selle kontsentratsioon suureneb p\u00f5letike korral.<\/p>\n\n\n\n

Uuritav materjal, selle v\u00f5tmine, saatmine ja s\u00e4ilitamine<\/strong><\/p>\n\n\n\n

<\/td>Katsuti<\/strong><\/td>Geeli ja h\u00fc\u00fcbimisaktivaatoriga katsuti (punane kollase r\u00f5ngaga v\u00f5i kollane kork) v\u00f5i geeliga LH-katsuti (roheline kollase r\u00f5ngaga v\u00f5i heleroheline kork)<\/td><\/tr>
<\/td>S\u00e4ilivus<\/strong><\/td>Seerum\/plasma toatemperatuuril kaks p\u00e4eva, +4 \u00b0C \u00fcks n\u00e4dal, -20 \u00b0C \u00fcks aasta<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Anal\u00fc\u00fcsi tegemise aeg:<\/strong> \u00f6\u00f6p\u00e4evaringselt<\/p>\n\n\n\n

Anal\u00fc\u00fcsimeetod:<\/strong> elektrokemoluminestsents-immuunmeetod (ECLIA)<\/p>\n\n\n\n

Referentsv\u00e4\u00e4rtused                               <\/strong><\/p>\n\n\n\n

<\/td>< 1 a<\/strong><\/td><\/td>12\u2013327 \u00b5g\/L<\/td><\/tr>
<\/td>1 a \u2013 < 4 a<\/strong><\/td><\/td>6\u201367 \u00b5g\/L<\/td><\/tr>
<\/td>4 a \u2013 < 7 a<\/strong><\/td><\/td>4\u201367 \u00b5g\/L<\/td><\/tr>
<\/td>7 a \u2013 < 13 a<\/strong><\/td>M<\/td>14\u2013124 \u00b5g\/L<\/td><\/tr>
<\/td>7 a \u2013 < 13 a<\/strong><\/td>N<\/td>7\u201384 \u00b5g\/L<\/td><\/tr>
<\/td>13 a \u2013 < 18 a<\/strong><\/td>M<\/td>14\u2013152 \u00b5g\/L<\/td><\/tr>
<\/td>13 a \u2013 < 18 a<\/strong><\/td>N<\/td>13\u201368 \u00b5g\/L<\/td><\/tr>
<\/td>18 a \u2013 < 61 a<\/strong><\/td>M<\/td>30\u2013400 \u00b5g\/L<\/td><\/tr>
<\/td>18 a \u2013 < 61 a<\/strong><\/td>N<\/td>13\u2013150 \u00b5g\/L<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Eakamatel patsientidel v\u00f5ivad esineda referentsvahemikest k\u00f5rgemad ferritiini v\u00e4\u00e4rtused.<\/p>\n\n\n\n

N\u00e4idustus ja kliiniline t\u00e4hendus<\/strong><\/p>\n\n\n\n

Rauapuuduse ja rauapuudusaneemia diagnostika ja ravi j\u00e4lgimine. Rauavarude seire krooniliste neeruhaiguste korral. Imikute, rasedate rauapuuduse s\u00f5eltestimine. Lisauuring hemokromatoosi diagnostikas ja ravi seires.<\/p>\n\n\n\n

Ferritiin on koos transferriini lahustuvate retseptoritega (Transf-sR) rauapuudusaneemia diagnoosimise valiktestiks.<\/p>\n\n\n\n

Ferritiini kontsentratsiooni v\u00e4henemine<\/em><\/p>\n\n\n\n

Ferritiini kontsentratsioon seerumis v\u00e4heneb rauapuuduse prelatentses faasis, mille korral v\u00e4heneb raua hulk depoodes. Rauapuuduse s\u00fcvenedes ja rauapuudusliku er\u00fctropoeesi kujunedes lisandub madalale ferritiininivoole transferriini lahustuvate retseptorite taseme t\u00f5us (hemoglobiin on veel referentsvahemikus). Normaalsed ferritiini v\u00e4\u00e4rtused ei v\u00e4lista rauapuudust (ferritiin on \u00e4geda faasi valk).<\/p>\n\n\n\n

Rauapuuduse peamised p\u00f5hjused on raua v\u00e4hesus toidus, krooniline verekaotus (meno- ja metrorraagia, verejooks gastrointestinaaltraktist), v\u00e4henenud imendumine, suurenenud tarbimine (rasedus, laktatsioon, kiire kasvuperiood).<\/p>\n\n\n\n

Ferritiini kontsentratsiooni suurenemine<\/em><\/p>\n\n\n\n

Ferritiini kontsentratsioon seerumis suureneb raualadestuse (hemosideroos, hemokromatoos) korral. Ferritiini taseme t\u00f5us koos transferriini saturatsiooniga \u2265 45% viitab p\u00e4rilikule hemokromatoosile.<\/p>\n\n\n\n

Ferritiin kuulub \u00e4geda faasi valkude hulka ja selle tase on t\u00f5usnud \u00e4gedate ja krooniliste maksahaiguste, infektsioonide ja p\u00f5letike (artriidid), pahaloomuliste kasvajate (\u00e4ge leukeemia, Hodgkini t\u00f5bi, kopsu-, maksa-, k\u00e4\u00e4rsoole- ja eesn\u00e4\u00e4rmev\u00e4hk, ka maksametastaasid), aneemiate (megaloblastiline, hemol\u00fc\u00fctiline, sideroblastiline aneemia, talasseemia, sf\u00e4rots\u00fctoos, porphyria cutanea tarda<\/em>), samuti h\u00fcpert\u00fcreoidismi ja m\u00fcokardiinfarkti korral.<\/p>\n\n\n\n

Terminaalse neerupuudulikkuse korral on tavap\u00e4rased ferritiini v\u00e4\u00e4rtused > 1000 \u00b5g\/L ja nendel patsientidel viitavad rauapuudusele v\u00e4\u00e4rtused < 200 \u00b5g\/L.<\/p>\n\n\n\n

Muud m\u00f5jutavad tegurid<\/em><\/p>\n\n\n\n

Lisaks p\u00f5hjustavad ferritiininivoo t\u00f5usu hemol\u00fc\u00fcs, hiljutine vere\u00fclekanne, prooviv\u00f5tule eelnev rauarohke toidu s\u00f6\u00f6mine, alkohol, ravimid (rauapreparaadid, peroraalsed kontratseptiivid).<\/p>\n\n\n\n

Vt ka: Raud<\/a>
Transferriin<\/a>
Transferriini lahustuvad retseptorid<\/a><\/p>\n\n\n\n

Koostaja: Kaja Vaagen
Muudetud 06.09.2023<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Kliinilise keemia ja laboratoorse hematoloogia osakond Ferritiin on rauda sisaldav intratsellulaarne valk, mis on organismi raua depoovorm. Ferritiini on k\u00f5ige enam hepatots\u00fc\u00fctides ning maksa, p\u00f5rna ja luu\u00fcdi makrofaagides. Seda on samuti l\u00fcmfots\u00fc\u00fctides, fibroblastides ja k\u00fcpsevates er\u00fctroblastides. V\u00e4hesel m\u00e4\u00e4ral tsirkuleerib ferritiini veres ja kuna seerumi ferritiin p\u00e4rineb p\u00f5hiliselt rauadepoodest, siis on seerumi ferritiini v\u00e4\u00e4rtus rauadepoode t\u00e4itumuse […]<\/p>\n","protected":false},"author":36,"featured_media":0,"parent":7023,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-9925","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nFerritiin (S,P-Fer) - \u00dchendlabor<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/aneemia-uuringud\/ferritiin-sp-fer\/\" \/>\n<meta property=\"og:locale\" content=\"et_EE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ferritiin (S,P-Fer) - \u00dchendlabor\" \/>\n<meta property=\"og:description\" content=\"Kliinilise keemia ja laboratoorse hematoloogia osakond Ferritiin on rauda sisaldav intratsellulaarne valk, mis on organismi raua depoovorm. 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Ferritiini on k\u00f5ige enam hepatots\u00fc\u00fctides ning maksa, p\u00f5rna ja luu\u00fcdi makrofaagides. Seda on samuti l\u00fcmfots\u00fc\u00fctides, fibroblastides ja k\u00fcpsevates er\u00fctroblastides. 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