{"id":9975,"date":"2024-10-10T15:08:23","date_gmt":"2024-10-10T13:08:23","guid":{"rendered":"https:\/\/www.kliinikum.ee\/yhendlabor\/?page_id=9975"},"modified":"2025-12-21T17:26:53","modified_gmt":"2025-12-21T15:26:53","slug":"transferriin-sp-transf","status":"publish","type":"page","link":"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/aneemia-uuringud\/transferriin-sp-transf\/","title":{"rendered":"Transferriin (S,P-Transf)"},"content":{"rendered":"\n

<\/p>\n\n\n\n

Kliinilise keemia ja laboratoorse hematoloogia osakond<\/em><\/p>\n\n\n\n

Transferriin <\/strong>on maksas ja v\u00e4iksemal m\u00e4\u00e4ral retikuloendoteliaals\u00fcsteemis, testistes ning ovaariumides s\u00fcnteesitav beeta-1-globuliin, mille peamiseks \u00fclesandeks organismis on raua transport. Transferriin on ka nn negatiivne \u00e4geda faasi valk \u2013 tema kontsentratsioon v\u00e4heneb p\u00f5letike korral. Transferriin seob p\u00f6\u00f6rduvalt paljusid pol\u00fcvalentseid katioone, millest ainult raua ja vase sidumisel on f\u00fcsioloogiline t\u00e4hendus. \u00dcks transferriini molekul seob kaks rauaiooni. Tervetel inimestel on kasutusel umbes kolmandik transferriini rauasidumisv\u00f5imest. Transferriini rauak\u00fcllastusaste on arvutatav vastavalt valemile:<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Uuritav materjal, selle v\u00f5tmine, saatmine ja s\u00e4ilitamine<\/strong><\/p>\n\n\n\n

Patsient ei tohi kaks p\u00e4eva enne proovi v\u00f5tmist kasutada suukaudseid rauapreparaate!<\/p>\n\n\n\n

<\/td>Katsuti<\/strong><\/td>Geeli ja h\u00fc\u00fcbimisaktivaatoriga katsuti (punane kollase r\u00f5ngaga v\u00f5i kollane kork) v\u00f5i geeliga LH-katsuti (roheline kollase r\u00f5ngaga v\u00f5i heleroheline kork)<\/td><\/tr>
<\/td>S\u00e4ilivus<\/strong><\/td>Seerum\/plasma toatemperatuuril ja +4 \u00b0C kaheksa p\u00e4eva, -20 \u00b0C kuus kuud<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Anal\u00fc\u00fcsi tegemise aeg:<\/strong> \u00f6\u00f6p\u00e4evaringselt<\/p>\n\n\n\n

Anal\u00fc\u00fcsimeetod:<\/strong> immuunturbidimeetriline meetod<\/p>\n\n\n\n

Referentsv\u00e4\u00e4rtused<\/strong><\/p>\n\n\n\n

<\/td>< 9 n<\/strong><\/td>1,11\u20132,43 g\/L<\/td><\/tr>
<\/td>9 n \u2013 < 1 a<\/strong><\/td>1,15\u20133,52 g\/L<\/td><\/tr>
<\/td>1 a \u2013 < 19 a<\/strong><\/td>2,38\u20133,66 g\/L<\/td><\/tr>
<\/td>\u2265 19 a<\/strong><\/td>2,0\u20133,6 g\/L<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Transferriini k\u00fcllastatus 16\u201345%<\/p>\n\n\n\n

N\u00e4idustus ja kliiniline t\u00e4hendus<\/strong><\/p>\n\n\n\n

Hemokromatoosi diagnoosimine. Koos raua m\u00e4\u00e4ramisega rauavaegusaneemia diagnoosimine ning eristamine kroonilise haiguse puhusest aneemiast.<\/p>\n\n\n\n

Rauavaegusaneemiate korral on seerumi transferriinisisaldus suurenenud, kuid valk on v\u00e4hem k\u00fcllastatud rauaga (transferriini k\u00fcllastatus < 16%), sest seerumi rauasisaldus on madal. Kroonilise haiguse korral, kui on h\u00e4iritud raua l\u00fclitumine er\u00fctrots\u00fc\u00fctide koostisesse, on tase referentspiirides v\u00f5i madalam, kuid valk on rauaga tugevasti k\u00fcllastatud (transferriini k\u00fcllastatus referentspiirides). Raua liia esinemisel organismis on transferriini kontsentratsioon normaalne v\u00f5i v\u00e4henenud, kuid transferriini k\u00fcllastatus on \u00fcle 55% ja v\u00f5ib ulatuda kuni 100%-ni. Transferriini k\u00fcllastatus meestel \u00fcle 60% ja naistel \u00fcle 50% viitab kongenitaalsele hemokromatoosile. Transferriini tase v\u00f5ib t\u00f5usta rauapreparaatide tarvitamisel, raseduse ajal ning suukaudsete rasestumisvastaste preparaatide tarvitamisel.<\/p>\n\n\n\n

Madalamad transferriini v\u00e4\u00e4rtused v\u00f5ivad olla tingitud s\u00fcnteesi v\u00e4henemisest (krooniline maksahaigus, vaegtoitumus), valgukaotusest (nefrootiline s\u00fcndroom, valgukaotuslikud enteropaatiad) v\u00f5i kroonilise haiguse aneemiast (infektsioonid, s\u00fcsteemsed sidekoehaigused, pahaloomulised kasvajad). Kaasas\u00fcndinud atransferrineemia korral kaasub v\u00e4ga madalate transferriini v\u00e4\u00e4rtustega raua liig organismis ja raske h\u00fcpokroomne aneemia, mis ei allu ravile rauapreparaatidega.<\/p>\n\n\n\n

Vt ka: Ferritiin<\/a>
Raud<\/a>
Transferriini lahustuvad retseptorid<\/a><\/p>\n\n\n\n

<\/p>\n\n\n\n

Koostaja: Sirje Leedo
Muudetud 18.03.2021<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Kliinilise keemia ja laboratoorse hematoloogia osakond Transferriin on maksas ja v\u00e4iksemal m\u00e4\u00e4ral retikuloendoteliaals\u00fcsteemis, testistes ning ovaariumides s\u00fcnteesitav beeta-1-globuliin, mille peamiseks \u00fclesandeks organismis on raua transport. Transferriin on ka nn negatiivne \u00e4geda faasi valk \u2013 tema kontsentratsioon v\u00e4heneb p\u00f5letike korral. Transferriin seob p\u00f6\u00f6rduvalt paljusid pol\u00fcvalentseid katioone, millest ainult raua ja vase sidumisel on f\u00fcsioloogiline t\u00e4hendus. \u00dcks […]<\/p>\n","protected":false},"author":36,"featured_media":0,"parent":7023,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-9975","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nTransferriin (S,P-Transf) - \u00dchendlabor<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kliinikum.ee\/yhendlabor\/kasiraamat\/aneemia-uuringud\/transferriin-sp-transf\/\" \/>\n<meta property=\"og:locale\" content=\"et_EE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Transferriin (S,P-Transf) - \u00dchendlabor\" \/>\n<meta property=\"og:description\" content=\"Kliinilise keemia ja laboratoorse hematoloogia osakond Transferriin on maksas ja v\u00e4iksemal m\u00e4\u00e4ral retikuloendoteliaals\u00fcsteemis, testistes ning ovaariumides s\u00fcnteesitav beeta-1-globuliin, mille peamiseks \u00fclesandeks organismis on raua transport. 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