Glomeeruli basaalmembraani vastane IgG (S-GBMA IgG)
Immuunanalüüsi osakond
Glomeeruli basaalmembraani vastase IgG sihtantigeeniks on IV tüüpi kollageeni alfa-3 ahel, mis asub peamiselt glomeerulite basaalmembraanis ja kopsualveoolides.
Uuritav materjal, selle võtmine, saatmine ja säilitamine
Katsuti
Geeli ja hüübimisaktivaatoriga katsuti (punane kollase rõngaga või kollane kork)
GBMA IgG esinemine on seotud kiiresti progresseeruva glomerulonefriidiga, peamiselt anti-GBM glomerulonefriidi ja Goodpasture’i sündroomiga (antikehi esineb 80–90% patsientidest). Harva leitakse neid autoantikehi kopsu hemorraagiaga patsientidel, kellel glomerulonefriiti ei kaasu.
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